Skip to content

Free Standard Shipping

|

Money Back Guarantee

|

Get 10%

|

Shipping Within the USA

Free standard shipping applies to all U.S. mainland orders above $49 and free express shipping on all U.S. orders above $100 (excludes Alaska, Hawaii, Puerto Rico, and the US Virgin Islands).

For orders under $49, we offer Flat Rate Standard Shipping for $6.99. With standard shipping, allow for 1-2 business days to process the order and 3-5 business days for delivery.

We also offer Flat Rate Express Shipping. Flat-Rate Express Shipping is $14.99. Please allow for 1-2 business days to process the order and 2 business days for delivery.

International Shipping

At this time we offer shipping to the customers in United States (including Hawaii, Alaska, Puerto Rico, Guam, Palau, and USVI) and internationally we are shipping to the United Kingdom and Canada. We are continuously working on it and plan to expand our international shipping to more countries in the future.

Money Back Guarantee

DMoose Return Policy:

  • Enjoy a 30-day money-back guarantee on all purchases.
  • Full refunds available if not satisfied—contact us within 30 days of receipt.
  • For returns, contact support@dmoose.com or call (833) 366-6733.

Extended Holiday Returns:

  • Orders from Nov 1 - Dec 31, 2023, can be returned until Jan 31, 2024.

Warranty Information:

  • 1-year warranty on all equipment.
  • Lifetime warranty on all belts.

Please reach out to our customer service for any return inquiries/claim a warranty or go to help.dmoose.com

Money Back Guarantee

DMoose Return Policy:

  • Enjoy a 30-day money-back guarantee on all purchases.
  • Full refunds available if not satisfied—contact us within 30 days of receipt.
  • For returns, contact support@dmoose.com or call (833) 366-6733.

Extended Holiday Returns:

  • Orders from Nov 1 - Dec 31, 2023, can be returned until Jan 31, 2024.

Warranty Information:

  • 1-year warranty on all equipment.
  • Lifetime warranty on all belts.

Please reach out to our customer service for any return inquiries/claim a warranty or go to help.dmoose.com

Free Standard Shipping

|

Money Back Guarantee

|

Get 10%

|

Shipping Within the USA

Free standard shipping applies to all U.S. mainland orders above $49 and free express shipping on all U.S. orders above $100 (excludes Alaska, Hawaii, Puerto Rico, and the US Virgin Islands).

For orders under $49, we offer Flat Rate Standard Shipping for $6.99. With standard shipping, allow for 1-2 business days to process the order and 3-5 business days for delivery.

We also offer Flat Rate Express Shipping. Flat-Rate Express Shipping is $14.99. Please allow for 1-2 business days to process the order and 2 business days for delivery.

International Shipping

At this time we offer shipping to the customers in United States (including Hawaii, Alaska, Puerto Rico, Guam, Palau, and USVI) and internationally we are shipping to the United Kingdom and Canada. We are continuously working on it and plan to expand our international shipping to more countries in the future.

Money Back Guarantee

DMoose Return Policy:

  • Enjoy a 30-day money-back guarantee on all purchases.
  • Full refunds available if not satisfied—contact us within 30 days of receipt.
  • For returns, contact support@dmoose.com or call (833) 366-6733.

Warranty Information:

  • 1-year warranty on all equipment.
  • Lifetime warranty on all belts.

Please reach out to our customer service for any return inquiries/claim a warranty or go to help.dmoose.com

Money Back Guarantee

DMoose Return Policy:

  • Enjoy a 30-day money-back guarantee on all purchases.
  • Full refunds available if not satisfied—contact us within 30 days of receipt.
  • For returns, contact support@dmoose.com or call (833) 366-6733.

Warranty Information:

  • 1-year warranty on all equipment.
  • Lifetime warranty on all belts.

Please reach out to our customer service for any return inquiries/claim a warranty or go to help.dmoose.com

Promising Male Birth Control Drug Shows Fast Action in Laboratory Tests

DMOOSE

Promising Male Birth Control Drug Shows Fast Action in Laboratory Tests
Table Of Contents
/g>

A team of researchers at Weill Cornell Medicine has developed a new drug that could offer a promising new form of male contraception. The drug, a soluble adenylyl cyclase (sAC) inhibitor, is designed to stop sperm from swimming and maturing, preventing pregnancies from occurring. 

How Does It Work

The drug works by blocking a molecular switch that triggers sperm to swim and search for an egg, resulting in male mice becoming infertile within 30 minutes of receiving the drug. The study was published in Nature Communications.

The new drug offers hope in the quest for better birth control for men, who currently have two options: condoms or a vasectomy. Many experts in the field see the development of new forms of male contraception as increasingly urgent, especially given the recent Supreme Court decision to overturn Roe vs. Wade. There is a growing demand for more contraceptives, including ones that shift the burden of contraception from women to men.

One of the key advantages of the new drug is that it is designed to be an on-demand contraceptive. Most other male contraceptives that are currently in development, such as hormone-based approaches, take weeks or months to start working, and they require a daily pill or a gel that must be rubbed into the skin. 

This makes them less attractive to some men, who may find the requirement of long-term use unappealing. By contrast, the sAC inhibitor can be taken just before intercourse, making it a more convenient and accessible option.

The Challenges

The development of new male contraceptives has been challenging for a number of reasons. First and foremost, any new contraceptive must be highly effective, easy to tolerate, and extremely safe since it will be given to healthy people. 

In addition, many scientists have doubted that men would be willing to take such drugs. Finally, targeting sperm production with a drug has turned out to be a difficult task because many of the proteins involved are important for other bodily functions.

The discovery of the sAC inhibitor has given researchers new hope, however. The team at Weill Cornell Medicine began exploring the potential of sAC inhibitors as a form of birth control almost two decades ago after it became clear that the sAC molecule plays a crucial role in sperm activation. 

However, interest in the molecule from drug companies waned over the years, and it wasn't until 2018 that the team began to focus on it again. At that point, Melanie Balbach, a postdoctoral scientist, showed her bosses a video of mouse sperm that had been injected with an experimental drug developed for eye disease. 

The video showed the sperm just twitching rather than swimming as they normally would. This result gave the researchers hope that blocking sAC could be a viable way to develop a male contraceptive.

The latest study shows that the improved version of the sAC inhibitor is highly effective at preventing pregnancies in mice, and it can be taken as an injection rather than a pill. The researchers are now working on developing the most potent and optimal form of the drug so that it can be taken as a pill and will prevent pregnancy for up to 12 hours. They have founded a start-up company called Sacyl6. 

Pharmaceuticals, to help move the research forward once the best version of the drug has been identified.

While the development of a new male contraceptive is exciting, it is important to note that it will be many years before the drug becomes available to the public. John Amory, a physician, and researcher developing male contraceptives at the University of Washington said that the process of developing a new contraceptive can be slow and that there is a lack of interest from the industry in turning academic insights into commercial drugs. Nonetheless, the team at Weill Cornell Medicine is hopeful that the sAC inhibitor could be a game-changer for male contraception, and they are!

Healthier and Happier Life is One Step Away.

Get information on health, fitness and wellness with our weekly newsletter.

  • 6 New Year Resolutions You Should Take for a Healthy Life

    Now that 2022 has almost come to an end, you must be contemplating what you have achieved so far. Do not be dishea...

  • 10 Healthy Tips on How to Stay Fit in College

    Ah, the pressures of college -all-nighters, coffee binges, and hangry snacks. We know how hard it can be to stay o...

  • 7 Nutrition Rules You May Be Breaking Without Realizing as a Beginner

    When it comes to nutrition, it's easy to focus on what you should be doing. Eat your vegetables, drink plenty of w...

  • 8 Best Natural Ingredients for Weight Loss That Works

    Are you tired of fad diets and searching for a natural way to shed extra pounds? Look no further! Several powerful...

  • 5 Best Arm Exercises to Build Muscle

    Building arm muscles is a common goal for most fitness enthusiasts. Not only do more muscular arms look i...

  • 6 Best Leg Exercises That Will Get You in Shape Fast

    Skipping leg day may be tempting but think of it like this; strong legs not only look good but are also essential ...

  • 8 Fast Bodyweight Exercises for Weight Loss
  • Ice Cold Baths for Quick Fat Burn — Fact or Myth?

    History tells us that people from different cultures worldwide have been using ice-cold baths for various health b...

  • SEAD: A Promising Dietary Approach for Mental Health - Evidence from a European Study

    A recent study published in Molecular Psychiatry investigated the association between the South European Atlantic ...

  • Evidence-Based Approaches to Preventing and Treating Muscle Soreness

    Muscle soreness is a natural consequence of intense or unfamiliar exercise. Referred to as delayed onset muscle so...

  • Start your fitness journey today!

    Take an extra 10% off your order.

    reach out

    Toll Free: (833) 366-6733

    support@dmoose.com

    5700 Crooks Road, Troy, Michigan 48098

    *By submitting this form you are signing up to receive our emails and can unsubscribe at any time.